Dr. Kashif Bashir

Dr. Kashif Bashir is a Pharmacist by profession and has work experience in pharmaceutical industry, research (nationally and internationally) as well as academia. He is engaged with research for more than 10 years working on various aspects of medicinal plants. His major areas of expertise are tandem mass spectrometry based metabolomics, chemical profiling, chromatographic isolation techniques (column chromatography, preparative TLC, analytical HPLC, semi-preparative HPLC and preparative HPLC) for natural products. He has also expertise in structure elucidation of natural products using various spectroscopic (NMR, FT-IR, UV) and spectrophotometric techniques (mass spectrometry). He also worked as visiting scholar at University of California, Santa Cruz, USA in the lab of Prof. Phillip Crews, Distinguished Professor of Chemistry and Biochemistry from December 2019 to Feb 2021. During his stay at University of California, Santa Cruz he worked on advanced chromatographic, spectroscopic techniques and cutting edge techniques in natural products metabolomics using Global Natural Products Social (GNPS) Molecular Networking.

• Kashif Bashir, Sadia Naz, Umar Farooq, Fazli Wahid, Abdul Jabbar Shah, Erin P. McCauley, Phillip Crews, Taous Khan 2021. Assessing the ethnobotanical potential of Carissa opaca berries by merging outcomes from metabolomics profiling, enzyme assays, and in silico docking studies. Food Chemistry, p.130259. https://doi.org/10.1016/j.foodchem.2021.130259 .
• Kashif Bashir, Sadia Naz, Hafiz Majid Rasheed, Umar Farooq, Abdul Jabbar Shah, Erin P. McCauley, Phillip Crews, Taous Khan (2022). Tandem high resolution mass spectrometry based phytochemical composition of Sauromatum guttatum tubers and its enzyme inhibitory potential with molecular docking. Journal of Chromatography A, 463055. https://doi.org/10.1016/j.chroma.2022.463055 .
• Ali Said, Fazli Wahid, Kashif Bashir, K., Hafiz Majid Rasheed, Taous Khan, Zohaib Hussain& Sami Siraj (2019). Sauromatum guttatum extract promotes wound healing and tissue regeneration in a burn mouse model via up-regulation of growth factors. Pharmaceutical Biology, 57(1), 736–743. https://doi.org/10.1080%2F13880209.2019.1676266 .
• Anam Saeed, Kashif Bashir, Rahila Qayyum, Abdul Jabbar Shah, Taous Khan, (2022). Antihypertensive activity in high salt induced hypertensive rats and LC-MS/MS-based phytochemical profiling of Melia azedarach L. (Meliaceae) leaves. BioMed Research International, 2791874. https://doi.org/10.1155/2022/2791874 .
• Erin P. McCauley, Ivette C Piña, Alyssa D. Thompson, A. D., Kashif Bashir, Mariam Weinberg, Shannon L. Kurz, S. L, & Phillip Crews. (2020). Highlights of marine natural products having parallel scaffolds found from marine-derived bacteria, sponges, and tunicates. The Journal of Antibiotics 73, 504–525 (2020). https://doi.org/10.1038/s41429-020-0330-5

• Pharmaceutical chemistry
• Chromatographic techniques (Analytical HPLC, Semi Prep HPLC, Prep HPLC)
• LC-MS/MS based Metabolomics profiling of natural products
• Natural product chemistry (Plants and marine natural products)
• Phytochemistry (Chemical Profiling)
• Structural elucidation of natural products (Mass Spectrometry (LC-MS, GC-MS, NMR, FT-IR)
• Enzyme inhibition
• Molecular docking

• Anti-breast cancer activity of Phytochemical constituent from Sauromatum guttatum tubers, COMSATS University Islamabad, 0.2 M PKR.

• Isolation, Identification and In Silico Studies on Enzyme Inhibitors from Sauromatum guttatum and Carissa opaca, IRSIP, Higher Education Commission of Pakistan at University of California Santa Cruz, CA, USA, 12,550 (USD)

• 1^st Poster Presentation Award at 1^st National Conference on Current Updates in Pharmacy Profession and Research” July 29-30, 2019